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07/29/2010 Study Identifies Molecular Mechanism Triggering Parkinson's Disease
San Jose Mercury News -
Scientists have identified a molecular pathway responsible for the death of key cells that causes Parkinson's disease, a discovery that could open the door to new treatments.
07/13/2010 Vitamin D May Lower Parkinson's Risk
WebMD -
A new study published in the Archives of Neurology has found that higher levels of vitamin D may reduce the risk of developing Parkinson's disease.
06/23/2010 Promise Seen for Detection of Alzheimer's
New York Times -
Researchers may have developed a biomarker for Alzheimer's disease that can help with diagnosis and drug development. The technique is similar to an approach to develop a PD biomarker, supported by MJFF.
06/22/2010 Positive Results Announced in Trial of Gene Therapy for PD
Study participants who received an investigational gene therapy for advanced Parkinson's disease in a Phase 2 trial experienced statistically significant improvements in off-medication motor scores.
06/21/2010 Seeking to Illuminate the Mysterious Placebo Effect
New York Times -
Dr. Tor Wager, a recipient of MJFF funding to study the placebo effect, is profiled by the New York Times for his work in this area of research.
06/17/2010 In Boulder, a Simulation Demonstrates What It's Like to Have Parkinson's Disease
The Daily Camera -
To help people understand the daily battles of the more than 17,000 Parkinson's sufferers in the Rocky Mountain region, the Parkinson Association of the Rockies set up simulations Wednesday on Boulder's Pearl Street Mall.
06/14/2010 Awaiting the Genome Payoff
The New York Times -
Ten years after President Bill Clinton announced completion of the first draft of the Human Genome Project, in June 2000, its application to drug development is still, at best, a work in progress.
06/14/2010 Spinal Cord Stimulation May Benefit Parkinson's Patients
EurekAlert! -
A new study from Rhode Island Hospital indicates that spinal cord stimulation may be able to modulate Parkinson's disease symptoms.
06/14/2010 Pesticides, Genes Interact to Up Risk of Parkinson's
Reuters -
Men with certain genetic variations who were exposed to some toxic pesticides have an increased risk of developing PD, according to a new study published in the Archives of Neurology.
06/12/2010 A Decade Later, Genetic Map Yields Few New Cures
The New York Times -
Ten years after President Bill Clinton announced that the first draft of the human genome was complete, medicine has yet to see any large part of the promised benefits.
06/11/2010 Drug Makers Share Data from Failed Alzheimer's Trials
Wall Street Journal -
A group of major pharmaceutical companies will share pooled data from failed clinical trials to help improve drug development. The coalition aims to create similar pooled databases for Parkinson's disease.
06/10/2010 Parkinson's Disease Work-Related Disability Assessment
PAN -
Download and share a comprehensive form to document information about PD symptoms that may be helpful when applying for Social Security Disability Insurance or Supplemental Security Income.
06/03/2010 DBS Works in Two Sites for Parkinson's Disease
HealthDay -
A new study in the New England Journal of Medicine finds that people living with advanced Parkinson's disease can benefit from deep brain stimulation in either one of two sites in the brain.
05/14/2010 Desperately Seeking Cures
Newsweek -
More and more policymakers and patients are asking, where are the cures? The answer is that potential cures, or at least treatments, are stuck in the chasm between a scientific discovery and the doctor's office: what's been called the valley of death.
05/12/2010 Researchers Unlocking Learning Strategies in Parkinson's Patients
PhysOrg.com -
Researchers are a step closer to understanding how medications affect learning in patients with early-stage Parkinson's disease.
05/11/2010 Parkinson's Drugs Linked with Compulsive Behaviors
Reuters -
A recent study found that Parkinson's drugs can triple the odds that people develop impulse control problems such as gambling, binge eating and shopping sprees.
05/10/2010 Pramipexole Shows Promise for Treating Depression in Parkinson's Disease
PhysOrg.com -
A study published in The Lancet Neurology reports that pramipexole, a dopamine agonist, improves depressive symptoms in patients with Parkinson's disease.
05/06/2010 Endometrial Stem Cells Restore Brain Dopamine Levels
ScienceBlog -
In pre-clinical models of PD, endometrial stem cells injected into the brain appeared to take over the functioning of cells eradicated by the disease. The finding raises the possibility that women with Parkinson's could serve as their own stem cell donors.
05/03/2010 New Pre-clinical Model Mimics Parkinson's Earliest Symptoms
physorg.com -
Researchers funded by MJFF have created the first transgenic mouse model to display the earliest signs of Parkinson's disease.
04/28/2010 Ceregene Has Initiated a New Phase 1/2 Trial Of CERE-120 for Parkinson's Disease
Enrollment is proceeding in a new Phase 1/2 clinical study evaluating CERE-120, a gene therapy product that delivers the neurotrophic factor neurturin to dying neurons in Parkinson's patients.
04/28/2010 Deep Brain Stimulation for Advanced Parkinson's Disease
CTV News -
A new study published in The Lancet Neurology found that patients with advanced PD who underwent deep brain stimulation in addition to standard PD medications reported a better quality of life and improved mobility.
04/27/2010 UCB Gets Complete Response Letter from FDA Regarding Neupro
RTT News -
FDA has recommended reformulation of Neupro before making it available in the U.S. market for the treatment of Parkinson's disease and restless legs syndrome.
04/27/2010 As America Ages, Parkinson's -- Already Common -- Could Become Much More Widespread
The New York Daily News -
MJFF SAB member Warren Olanow discusses Parkinson's disease, including risk, signs and symptoms, treatment options and the critical importance of seeing a neurologist who specializes in movement disorders.
04/16/2010 Parkinson’s Disease 'Could Be Diagnosed by Voice Changes'
Telegraph.co.uk -
Parkinson’s disease could be diagnosed earlier by measuring changes in the sound of the voice, according to researchers.
04/09/2010 Obama to Appoint Boxer Ali's Wife to Commission for the Study of Bioethical Issues
The Associated Press -
The panel will advise the president on issues related to advances in biomedicine and similar areas of science and technology.
03/31/2010 For Some, Cycling Eases Parkinson's Symptoms
New York Times -
A patient with late stage Parkinson's disease is unable to walk but can ride a bicycle, surprising his doctor and other Parkinson's specialists.
03/31/2010 BioTechniques: Antibodies for Parkinson’s Disease Research Available for Validation
BioTechniques -
To expedite the antibody validation process, the Michael J. Fox Foundation is providing samples of antibodies that target a protein associated with Parkinson’s disease.
03/31/2010 Save the Date! 16th Annual Parkinson's Unity Walk
Come join thousands of people on Saturday, April 24, 2010 for the 16th Annual Parkinson's Unity Walk in Manhattan's beautiful Central Park.
03/30/2010 Judge Invalidates Human Gene Patent
The New York Times -
The decision, if upheld, could throw into doubt the patents covering thousands of human genes and reshape the law of intellectual property.
03/29/2010 Senate Officially Designates April as Parkinson's Awareness Month
Parkinson's Action Network -
The Parkinson's Action Network encourages you to use the momentum from the Senate’s designation and ask state and local leaders to raise awareness of Parkinson’s.
03/23/2010 The Health Bill's Cures for Research
ScienceInsider -
Buried within the 2400 pages of the landmark health care reform bill are three provisions that touch on clinical research.
03/15/2010 New Guideline Issued for Non-Motor Symptoms of Parkinson's Disease
American Academy of Neurology -
The American Academy of Neurology has issued a new guideline recommending the most effective treatments to help alleviate non-motor PD symptoms.
03/10/2010 Smoking Years Key Factor in Lower Parkinson's Risk
Reuters Health -
Several studies have shown that smokers have a lower risk of developing Parkinson's disease. A new study shows that it's how many years of smoking a person has under their belt -- rather than how much they smoke every day -- that matters.
03/05/2010 Deep Brain Stimulation for Early Parkinson’s Shows Promise
The Vanderbilt Reporter -
A Vanderbilt University study of deep brain stimulation for early Parkinson's disease has shown such promise that several other universities have signed on to plan a large-scale, multi-center trial.
03/04/2010 Parkinson's Limits Ability to Read Emotions
The New York Times -
New research suggests that Parkinson's disease may impair a person’s ability to read the emotions of others.
03/02/2010 'A Pathway' to Fight Parkinson's
Omaha World-Herald -
Researchers at the University of Nebraska Medical Center have developed a vaccine that reverses an experimental form of PD in pre-clinical models of the disease.
02/22/2010 Eisai Discontinues Phase 3 Trial of E2007 (Perampanel)
PipelineReview.com via Gerson Lehrman Group -
Experimental evidence and early clinical trials supported AMPA receptor blockade as a therapeutic option, but later studies failed to show a significant reduction in clinical "off" time compared to placebo.
02/15/2010 Stem Cell Alternatives Show Early Aging Abnormalities
USA Today -
A first head-to-head comparison of human embryonic stem cells with ones grown from skin cells revealed early aging and other abnormalities in the less-controversial alternatives.
02/10/2010 Voice Problems May Affect Social Life in Parkinson's
HealthDay News via U.S. News & World Report -
A new study finds that patients may be perceived as 'negative' due to disease-related changes in their speech.
02/08/2010 Obama's 'Restrained' 2011 Budget Would Not Freeze NIH
GenomeWeb Daily News -
The 2011 budget proposal indicates that the president sees research as a priority.
02/08/2010 Industrial Solvent Linked to Increased Risk of Parkinson's Disease
Los Angeles Times Blog -
A new study finds exposure to the industrial solvent trichloroethylene increases a person's risk of developing Parkinson's disease nearly sixfold.
02/03/2010 Become a Parkinson's Advocate in Your Community
If you live in the Washington, DC metropolitan area, join the 16th Annual Research and Public Policy Forum, a day of education and advocacy for the Parkinson's community hosted by the Parkinson's Action Network. For those outside the area, the Forum will also be Webcast live.
02/02/2010 Three Brain Diseases Linked by a Toxic Form of the Same Neural Protein
ScienceDaily -
For the first time, researchers have found that Parkinson's disease, Alzheimer's disease and Huntington's disease are linked by a toxic form of the same protein, called Elk-1.
02/01/2010 Positive Interim Results for Potential First-in-class Treatment for Parkinson’s Disease
BusinessWire -
The data from a Phase IIa study in 24 Parkinson’s patients showed statistically significant, dose-related changes in blood flow in regions of the brain known to be relevant to Parkinson’s.
01/27/2010 U.S. Parkinson's Rates Highest in Whites, Hispanics and Midwest, Northeast
ScienceDaily -
The largest epidemiological study of U.S. Parkinson's disease patterns has found that the disease is more common in the Midwest and the Northeast and is twice as likely to strike whites and Hispanics as blacks and Asians.
01/26/2010 Charles Mathias, Former U.S. Senator, Dies at 87
New York Times -
The champion of civil rights died at age 87 from complications of Parkinson's disease.
01/20/2010 Treadmill Training Improves Walking in Parkinson's
MedPage Today -
The technique leads to improvements in gait speed, stride length, and walking distance, but not gait cadence, according to researchers in Germany.
01/20/2010 Brain Abnormalities in Parkinson's Patients Develop Before Symptoms Occur
North Shore-Long Island Jewish (LIJ) Health System via EurekAlert! -
Scientists have new evidence that brain networks damaged in Parkinson's disease become abnormal a few years before symptoms appear.
01/13/2010 Parkinson's Patients Shed Light on Role of Reward Bias in Compulsive Behaviors
Eurek!Alert -
New research unravels the brain mechanisms underlying the ability of a standard drug treatment for Parkinson's to elicit compulsive behaviors in some patients.
01/13/2010 Art Rust, Jr., Pioneer in Sports Talk Radio, Dies at 82
The New York Times -
The pioneering New York radio sports talk show figure and sports historian died at 82 from complications of Parkinson’s disease.
01/12/2010 Reducing Dosage of Parkinson's Drugs Can Cause Symptoms Similar to Those of Cocaine Withdrawal
Science Daily -
New research shows that reducing the dosage of dopamine agonists can cause acute withdrawal symptoms including anxiety, panic attacks, depression, sweating, nausea, generalized pain, fatigue, dizziness and drug cravings.
01/11/2010 Brain Scans Can Give Early Diagnosis of Different Forms of Parkinsonism
Medical News Today -
Researchers report that PET scans can identify with high accuracy which form of Parkinsonism a patient has.
01/07/2010 PET Scans Predict Who Responds to Parkinson's Brain Cell Transplant Treatment
DOTmed.com -
New research indicates that PET scans can pick up a useful Parkinson's biomarker and help predict who will benefit from treatment with transplanted fetal neural tissue.
01/05/2010 Generic Pramipexole (Mirapex) Now Available to U.S. Parkinson's Patients
DrugStoreNews.com -
A generic drug maker has announced the availability of a treatment for the signs and symptoms of idiopathic Parkinson’s disease.
